2024 Week 3 NFL picks, odds, best bets from advanced model: This 5-way football parlay pays 25-1

The Week 3 NFL schedule features a full slate of 16 games with no teams favored by double-digits in the latest Week 3 NFL odds. Among the most notable Week 3 NFL matchups are Vikings vs. Texans (-2), Eagles vs. Saints (-2.5), and Cowboys vs. Ravens (-1). The Cowboys and Ravens entered the season with Super Bowl aspirations, but have gotten off to rocky starts. Both teams could use a win in Week 3, but which team should you include in your NFL parlay picks and NFL best bets?

Which NFL underdogs should you target when making Week 3 NFL betting picks, and which NFL favorites will cover the spread in Week 3? Before you make any Week 3 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 3 of the 2024 NFL season on an incredible 187-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 41-22 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has scoured the Week 3 NFL odds and locked in five confident NFL best bets. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 3 NFL picks at SportsLine.

Top Week 3 NFL picks

After simulating every game 10,000 times, the model is high on the Seattle Seahawks (-4.5) cover at home against the Miami Dolphins. Cross-country road trips are never easy in the NFL, and the Dolphins are currently in a state of uncertainty. Starting quarterback Tua Tagovailoa (concussion) was placed on Injured Reserve and Skylar Thompson is set to take over for the time being.

The Seahawks are 2-0 to start the season and have playmakers all over the field on both sides of the ball. Defensively, Seattle has one of the league’s best secondaries, which could make life difficult for Thompson. Offensively, the Seahawks have three star wide receivers (DK Metcalf, Tyler Lockett, and Jaxon Smith-Njigba) who are all threats to score every time they touch the ball. See which other NFL parlay picks to make here.  

How to make Week 3 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including a home underdog that covers the spread in well over 60% of simulations, defying oddsmakers everywhere. You can only see the model’s NFL Week 3 best bets and parlay at SportsLine.  

What are the model’s top Week 3 NFL picks, and which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 3 NFL best bets from a model on an 187-130 run on top-rated picks, and find out.